1. Name : Asst. Prof. Dr.Nuttawut Saelim

ผศ.ดร.ณัถวุฒิ แซ่ลิ้ม

Academic Position : Assistant Professor
Department : Department of Pharmacy Practice
Phone : 0 5596 1818
e-mail : nut456zz@hotmail.com

2. Contact Address

  • Faculty of Pharmaceutical Sciences, Naresuan University, Muang, Phitsanulok THAILAND 65000

    3. Educational Background

    • 2005 : Post doctoral ((Sep.-Dec.)) , University of Hamburg, Hamburg , Germany
    • 2004 : Post doctoral ((Sep.-Nov.)) , Toyama Medical and Pharmaceutical University , Japan
    • 2003 : Ph.D. (Cellular and Structural Biology) , University of Texas Health Science Center at San Antonio (UTHSCSA) , Thailand
    • 1998 : Pharm.D. (Doctor of Pharmacy) , University of Wisconsin , United States Of America
    • 1995 : M.S. (Food Sciences and Technology) , University of New South Wales , Australia
    • 1986 : B.S. (Bachelor of Sciences in Pharmacy) , Prince of Songkla University, , Thailand

    5. Publication / Books

      5.01 Research Publication
    • Khamlue, R. , Ounaroon, A. , Saelim, N. . 2012 . Purification and characterization of polysaccharides extracted from Tremella fuciformis and Auricularia auricular . MFUIC .
    • Khamlue, R. , Naksupan, N. , Ounaroon, A. , Saelim, N. . 2012 . Skin wound healing promoting effect of polysaccharides extracts from Tremella fuciformis and Auricularia auricula on the ex-vivo porcine skin wound healing model . International Proceedings of Chemical, Biological & Environmental Engineering IPCBEE . 43 : 93-98.
    • Chocron, E.S. , Sayre, N.L. , Holstein, D. , Saelim, N. , Ibdah, J.A. , Dong, L.Q. , Zhu, X. , Cheng, S.Y. , and Lechleiter, D.J. . 2012 . The Trifunctional Protein Mediates Thyroid Hormone Receptor-Dependent Stimulation of Mitochondria Metabolism . Molecular Endocrinology . 26 : 1117-1128.
    • Naksupan, N. , Saelim, N. , Taepavarapruk, P. , Taepavarapruk, N. . 2012 . Toxicity testing and wound healing efficacy of fibroin gel in animal model . MFUIC .
    • Sudchada, P. , Oo-puthinan, S. , Kerpin, O. , and Saelim, N. . 2010 . ABCB1 gene expression in peripheral blood mononuclear cells in healthy Thai males and females . Genet. Mol. Res. . 9 (2) : 1177-1185.
    • Suwanakitch, P. , Jeenapongsa, R. , Watanabe, H. , and Saelim, N. . 2008 . Comparison of Alzheimer disease-related gene expressions in differentiated and undifferentiated NG108-15 cells . Science Asia . 34 : 35-42.
    • Saelim, N. , Holstein, D. , Chocron, E.S. , Camacho, P. , Lechleiter, J.D. . 2007 . Inhibition of apoptotic potency by ligand stimulated thyroid hormone receptors located in mitochondria . Apoptosis . 12 : 1781-1794.
    • Saelim, N. . 2007 . Isolation of amyloid precursor protein (APP) gene from NG cell line . J. Health Res. . 21 (3) : 185-194.
    • Suwanakitch, P. , Jeenapongsa, R. , Tohda, M. , Saelim, N. , and Watanabe, H. . 2005 . Expression of Alzheimer-related genes in rat brain. 272: S1. . (Abstract number A1-031P). Federation of European Biochemical Societies Journal .
    • Hayashi, H, , Tohda, M. , Saelim, N. , Murakami, Y. , and Matsumoto, K. . 2005 . Influences of the mRNA expression of amyloid precursor protein and the related factors in primary cultured cortex cells . Journal of Pharmacological Sciences . 97 , 261 Page.
    • Saelim, N. et al. . 2004 . Nontranscriptional modulation of intracellular Ca2+ signaling by ligand stimulated thyroid hormone receptor . J Cell Biol . 167 (5) : 915-924.
    • Sudchada, P. , Saelim, N. , Oo-puthinan, S. , and Kerpin, O. . 2554 . Relationship between the 3435C>tT and 2677G>T/A polymorphisms and ABCB1 expression in peripheral blood mononuclear cells extracted from Thai males volunteers . Thai J of Genet . 4 (2) : 143-157.
    • Suwanakitch, P. , Jeenapongsa, R. , Saelim, N. , Tohda, M. , and Watanabe, H. . 2548 . Altered mRNA expression in ischemic rat brain . Thai Journal of Pharmacology . 27 , 52 หน้า.

      5.04 Poster | Oral Presentation
    • From Silk to Wound, . Poster Presentation: การประชุมเภสัชกรรมแห่งชาติ ครั้งที่ 8, , มหาวิทยาลัยนเรศวร พิษณุโลก.
    • Preparation and Charracterization of Silk Protein, Sericin & Fibroin, Isolated from Thai Yellow Silk Cocoons, . Poster presentation: งานประชุมวิชาการและนิทรรศการ “ทรัพยากรไทย: ก้าวสู่โลกกว้างอย่างมั่นใจ”, , มหาวิทยาลัยเทคโนโลยีราชมงคลอีสาน จังหวัดนครราชสีมา .
    • Development of Cell-based Model for NFAT Nuclear-cytoplasm Translocation for Bioactive Immuno-modulator Screening, . Poster presentation: PERCH-CIC congress VII: Chemistry, Environment and Society โดย Center of Excellence for Innovation in Chemistry (PERCH-CIC), , โรงแรมจอมเทียน พัทยา จังหวัดชลบุรี.
    • Skin Wound Healing Promoting Effect of Some Thai Medicinal Plant Extracts on ex-vivo Porcine Skin Wound Healing Model, . Poster presentation: PERCH-CIC congress VII: Chemistry, Environment and Society โดย Center of Excellence for Innovation in Chemistry (PERCH-CIC), , โรงแรมจอมเทียน พัทยา จังหวัดชลบุรี.
    • Isolation and Cultivation of Primary Skin Cell, Keratinocytes, Melanocytes, and Fibroblasts from Porcine Skins, . Poster Presentation: ณ โรงแรมระยองรีสอร์ท จังหวัดระยองโครงการพัฒนานักวิจัยไทยด้านวิทยาศาสตร์เคมีและเภสัช และ NRCT-CPS Conference V. Drug Discovery: Development of Drug Design-based Pharmaceutics จัดโดยศูนย์ PERCH-CIC คณะวิทยาศาสตร์มหาวิทยาลัยมหิดล , .
    • Isolation and Purification of Silk Proteins, Sericin and Fibroin, . Poster Presentation: การประชุมเภสัชกรรมแห่งชาติ ครั้งที่ 6 , , โรงแรมโกลเด้น ทิวลิป กรุงเทพฯ .
    • Cell Proliferation Effect of Thai Medicinal Plant Extracts on Primary Porcine Dermal Fibroblasts, . Poster Presentation: ประชุมวิชาการนเรศวรวิจัยครั้งที่ 6 , , มหาวิทยาลัยนเรศวร พิษณุโลก.
    • Skin Wound Healing Promoting Effect of Some Thai Medicinal Plant Extracts on ex-vivo Porcine Skin Wound Healing Model, . Poster Presentation: ประชุมวิชาการนเรศวรวิจัยครั้งที่ 6, , มหาวิทยาลัยนเรศวร พิษณุโลก.
    • Isolation and Cultivation of Primary Skin Cell, Keratinocytes, Melanocytes, and Fibroblasts from Porcine Skins, . Poster Presentation:ณ ศูนย์วิจัยเทคโนโลยีตัวอ่อนและเซลล์ต้นกำเนิด , , จัดโดยมหาวิทยาลัยเทคโนโลยีสุรนารี จังหวัดนครราชสีมา.
    • Characterization of Silk Protein Extracts, Sericin and Fibroin, from Thai Yellow Silk Cocoons for Medical Material Application, . Oral Presentation: ประชุมวิชาการนเรศวรวิจัยครั้งที่ 5, , มหาวิทยาลัยนเรศวร พิษณุโลก.

      5.05 Patent | Petty Patent
    • . Development of ex-vivo Porcine Skin Model and Optimizing ex-vivo Skin Tissue Culture Conditions. Petty Patent No. 0903000493 .
    • . Extraction and Purification Processes of Yellow Pigment, Sericin and Fibroin Proteins from Thai Yellow Silk Cocoons. Petty Patent No. 0903000191 .

    6. วิทยากร/กรรมการวิชาการนอกสถาบัน

    7. Ongoing Research

    • The role of silk protein extracts, sericin and fibroin, on wound healing using ex-vivo porcine skin model and in-vivo animal model.
    • Application of the ex-vivo porcine skin model for studying the effects of herbal extracts coated scaffolds on wound healing.
    • Application of the ex-vivo porcine skin model for melanoma study.
    • Application of the ex-vivo porcine skin model for screening of wound helaing promoting agents from herbal extracts.
    • Development of cell-based model of NFAT nuclear-cytoplasm translocation for screening of immunosuppressant and immuno-enhancing agents.
    • Acceleration of the wound healing rate by fibroin gel with targeting connexin43 antisense on ex-vivo pocine skin wound healing model.
    • Isolation, identification, and characterizatin of active compounds as wound healing promotor from black and white jelly fungi.
    • Searching for molecular targets and mechanism of actions of saponin glycosides from Bacopa monnieri on cardiovascular system.

    10. Training

    • 21 มกราคม 2558 , Human ethics training course “Middleton Foundation for Ethical Studies in Global Fellowship Program – MFES-GF” , Middleton Foundation for Ethical Studies in Global Fellowship Program. Bangkok , Thailand
    • 23 - 26 November 2014 , Human ethics training course “Embedding Ethics in National Health Research Systems” , Department of Science and Technology, Philippines Council for Health Research and Development, and FERCAP, Taal Vista Hotel, Tagaytay City, PHILIPPINES , Phillippine
    • 14 November 2014 , Human ethics training course “The United States Rottion of the MFES Global Fellowship Training” Middleton Foundation for Ethical Studies in Global Fellowship Program for Developing Capacity in Ethical Review , Olympia, Washington , United States Of America
    • 28 - 30 กันยายน 2555 , Human ethics training course “International Course on Surveying and Evaluating Ethical Review Practices” , the Faculty of Medicine, Chulalongkorn University Hosted by FERCAP-SIDCER-NECAST , Thailand
    • 13 กันยายน 2555 , Human ethics training course “Principle of Research Ethics Related to Human Subjects and Human Research Protocol Reviewing , FERCIT and Naresuan University, Naresuan University , Thailand
    • 2 - 4 มกราคม 2555 , การประชุมวิชาการ ”the 2nd Current Drug Development Internatioanl Conference 2012” , Phuket Graceland Resort and Spa Hotel, Phuket , Thailand
    • 27 - 30 กันยายน 2553 , Human ethics training course “International Course on Research Ethics” by WHO-TDR Clinical Coordination and Training Center , Thammasat University , Thailand
    • 25 July 2010 - 8 August 2010 , การประชุมวิชาการ Bio-Asia Project: PLANTASAFE 3rd Seminar, Forum on International Herbs Research and Development หัวข้อ Ex-vivo Porcine Skin Wound Healing Model and Its Appication , Urumqi, Xinjiang , China
    • 24 - 30 กรกฏาคม 2553 , the 4th SUT Stem Cell Workshop Proceedings: Stem Cell Innovation: a Milestone beyond Life Science Roadblocks , โรงแรม Suranaree University of Technology จังหวัดนครราชสีมา , Thailand
    • 13 - 19 กุมภาพันธ์ 2553 , Bio-Asia Project: PLANTASAFE 2nd Seminar, From Pharmacognosy to Pharmcology: Interative Approach of Natural Product Research หัวข้อ Ex-vivo Porcine Skin Wound Healing Model , Phitsanulok , Thailand
    • 12 - 14 มีนาคม 2552 , the 4th World Congress on Regenerative Medicine 2009 , โรงแรม Bangkok convention center and Centara grand hotel กรุงเทพฯ , Thailand
    • 1 September 2005 - 1 December 2005 , University of Hamburg, , Hamburg , Germany
    • 1 September 2004 - 1 November 2004 , • Toyama Medical and Pharmaceutical University, Toyama, JAPAN. September - November 2004. , Toyama , Japan
    • 19 - 30 June 1995 , United Nations Industrial Development Organization “Global Workshop on GMP in the Pharmaceutical Sector” Montreal, CANADA. , Montreal , Canada



  • Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, 65000, Thailand