1. Name : Assoc.Prof. Dr.Nanteetip Limpeanchob

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Academic Position : Associate Professor
Department : Department of Pharmacy Practice
Phone : 0 5596 1822
e-mail : nanteetipl@nu.ac.th

2. Contact Address

  • Faculty of Pharmaceutical Sciences, Naresuan University, Muang, Phitsanulok THAILAND 65000

    3. Educational Background

    • 2004 : Ph.D. (Pharmacology and Toxicology (Hons.)) , University of Kansas , United States Of America
    • 1996 : M.S. M.S. in Pharmacology (Master of Science in Pharmacology) , Mahidol University , Thailand
    • 1993 : B.Pharm. (Hons.) (Bachelor of Pharmacy (Hons.)) , Chiangmai University , Thailand

    4. Field of Experties

    • Neurosciences
    • Pharmacology
    • Toxicology

    5. Publication / Books

      5.01 Research Publication
    • Yamchuen, P. , Aimjongjun, S. , Limpeanchob, N. . 2014 . Oxidized low density lipoprotein increases acetylcholinesterase activity correlating with reactive oxygen species production . Neurochemistry International . 78 : 1-6.
    • Nimtrakul, P. , Atthi, R. , Limpeanchob, N. , Tiyaboonchai, W. . 2014 . Development of Pasteurella multocida-loaded microparticles for hemorrhagic septicemia vaccine . Drug Development and Industrial Pharmacy .
    • Hematulin, A. , Ingkaninan, K. , Limpeanchob, N. , Sagan, D. . 2014 . Ethanolic extract from Derris scandens Benth mediates radiosensitzation via two distinct modes of cell death in human colon cancer HT-29 cells . Asian Pacific Journal of Cancer Prevention . 15 (4) : 1871-1877.
    • Kongkeaw, C. , Dilokthornsakul, P. , Thanarangsarit, P. , Limpeanchob, N. , Norman, S.C. . 2014 . Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract . Journal of Ethnopharmacoogy, . 151 : 528-535.
    • Suphrom, N. , Srivilai, J. , Pumthong, G. , Khorana, N. , Waranuch, N. , Limpeanchob, N, , Ingkaninan, K. . 2014 . Stability studies of antiandrogenic compounds in Curcuma aeruginosa Roxb. extract . The Journal of pharmacy and pharmacology . 66 : 1282-1293.
    • Duangjai, A. , Ingkaninan, K. , Praputbut, S. , Limpeanchob, N. . 2013 . Black pepper and piperine reduce cholesterol uptake and enhance translocation of cholesterol transporter proteins . Journal of Natural Medicines . 67 : 303-310.
    • Pongcharoen, S. , Warnnissorn, P. , Lertkajornsin, O. , Limpeanchob, N. , Sutheerawattananonda, M. . 2013 . Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes . Biological Research . 46 : 39-45.
    • Aimjongjun, S. , Sutheerawattananonda, M. , Limpeanchob, N. . 2013 . Silk lutein extract and its combination with vitamin E reduce UVB-mediated oxidative damage to retinal pigment epithelial cells . Journal of Photochemistry and Photobiology B: Biology . 124 : 34-41.
    • Keawkorn, W. , Limpeanchob, N. , Tiyaboonchai, W, , Pongcharoen, S. , Sutheerawattananonda, M. . 2013 . The effect of dietary sericin on rats . Science Asia . 39 : 252-256.
    • Suphrom, N. , Pumthong, G. , Khorana, N. , Waranuch, N. , Limpeanchob, N. , Ingkaninan, K. . 2012 . Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb . Fitoterapia . 83 (5) : 864-871.
    • Kaewkorn, W, , Limpeanchob, N. , Tiyaboonchai, W. , Pongcharoen, S. , Sutheerawattananonda, M. . 2012 . Effects of silk sericin on the proliferation and apoptosis of colon cancer cells . Biological Research . 45 (1) : 45-50.
    • Kaewkon, W. , Aonsri, A. , Tiyaboonchai, W. , Pongcharoen, S. , Sutheerawattananonda, M. , Limpeanchob, N. . 2012 . Sericin consumption suppresses development and progression of colon tumorigenesis in 1,2-dimethylhydrazine-treated rats . Biologia . 67 (5) : 1007-1012.
    • Hematulin, A. , Ingkaninan, K. , Limpeanchob, N. , Sagan, D. . 2011 . Derris scandens Benth Extract Radiosensitizes HT-29 Colon Cancer Cells . Siriraj Medical Journal. . 63 (3) : 85-88.
    • Changwichit, K. , Khorana, N. , Suwanborirux, K. , Waranuch, N. , Limpeanchob, N. , Wisuitiprot, W. , Suphrom, N. , Ingkaninan, K. . 2011 . Bisindole alkaloids and secoiridoids from Alstonia macrophylla Wall. ex G. Don. . Fitoterapia . 82 (6) : 798-804.
    • Duangjai, A. , Ingkaninan, K. , Limpeanchob, N. . 2011 . Potential mechanisms of hypocholesterolemic effect of Thai spices/dietary extracts . Natural Product Research . 25 (4) : 341-352.
    • Tiyaboonchai, W. , Nimtrakul, P. , Limpeanchob, N. . 2010 . Development of Pasteurella multocida loaded alginate based microspheres . Naresuan University Journal . 18 (1) : 19-25.
    • Limpeanchob, N, , Trisat, K. , Duangjai, A. , Tiyaboonchai, W. , Pongcharoen, S. , Sutheerawattananonda, M. . 2010 . Sericin Reduces Serum Cholesterol in Rats and Cholesterol Uptake into Caco-2 Cells . Journal of Agricultural and Food Chemistry . 58 (23) : 12519-12522.
    • Donsing, P. , Limpeanchob, N. , Viyoch, J. . 2008 . Evaluation of the effect of Thai breadfruits heartwood extract on melanogenesis-inhibitory and antioxidant activities . Journal of Cosmetic Science . 59 : 41-48.
    • Limpeanchob, N. , Jaipan, S. , Rattanakaruna, S. , Phrompittayarat, W. , Ingkaninan, K. . 2008 . Neuroprotective Effect of Bacopa monnieri on Beta-amyloid-induced Cell Death in Primary Cortical Culture . Journal of Ethnopharmacology . 102 (1) : 112-117.
    • Temkitthawon, P. , Viyoch, J. , Limpeanchob, N. , Pongamornkul, W. , Sirikul, C. , Kumpila, A. , Suwanborirux, K. , Ingkaninan, K. . 2008 . Screening for phosphodiesterase inhibitory activity of Thai medicinal plants . Journal of Ethnopharmacology . 119 (2) : 214-217.
    • Tiyaboonchai, W. , Limpeanchob, N. . 2007 . Formulation and characterization of amphotericin B-chitosan-dextran sulfate nanoparticles . International Journal of Pharmaceutics . 329 (1) : 142-149.
    • Limpeanchob, N. , Tiyaboonchai, W. , Lamlertthon, S. , Viyoch, J. , Jaipan, S. . 2006 . Efficacy and toxicity of amphotericin B-chitosan nanoparticles in mice with induced systemic candidiasis . Naresuan University Journal . 14 (2) : 27-34.
    • Limpeanchob, N. . 2005 . Characterization of calcium-dependent phosphatase activity of calcineurin in cultured cortical neurons . Naresuan University Journal . 13 (1) : 45-50.
    • Wang, X. , Pal, R. , Chen, X.W. , Limpeanchob, N. , Kumar, K.N. , Michaelis, E.K. . 2005 . High intrinsic oxidative stress may underlie selective vulnerability of the hippocampal CA1 region . Brain Res Mol Brain Res. . 140 (1) : 120-126.
    • 2558 . Cholesterol lowering properties of Tiliacora triandra (Colebr.) Diels leaf extract in the Caco-2 cell line. . Naresuan Phayao Journal : 87-92.
    • 2554 . Daniel Sagan. Derris Scandens Benth Extract Radiosensitizes HT-29 Colon Cancer Cells. . Siriraj Medical Journal . 63 (3) : 85-88.
    • 2554 . Effects of curcuminoids on lipid peroxidation and antioxidant enzyme in rat microsome and HepG2 cells. . Thai Journal of Pharmacology . 33 (2) : 107-111.
    • 2554 . Protective effect of silk lutein extract and vitamin E on UV-B induced oxidative stress in retinal pigment epithelial cell damage. . Thai Journal of Pharmacology . 33 (2) : 60-63.
    • 2554 . Regulation of cholesterol transporter by black pepper and piperine. . Thai Journal of Pharmacology . 33 (1) : 44-47.

      5.04 Poster | Oral Presentation
    • Meephayoong, P. , Limpeanchob, N. . Immunostimulating activity of beta-glucan from Russula delica Fr. In RAW246.7 macrophage. (Poster Presentation Award), . Poster Presentation: The 4th, International Biochemistry and Molecular Biology Conference (BMB2014), Bridging ASEAN Biochemical Research Communities, April 2-3, 2014, , , Bangkok, Thailand.
    • Yancheun, P. , Limpeanchob, N. . Effect of oxidized low density lipoprotein on amyloid precursor protein processing in SH-SY5Y neuroblastoma cells, . Poster Presentation: The 4th, International Biochemistry and Molecular Biology Conference (BMB2014), Bridging ASEAN Biochemical Research Communities, , Bangkok, Thailand.
    • Activities and Mechanisms of Black Pepper and Piperine to Inhibit Cholesterol Uptake, . Oral Presentation: III International Symposium on Medicinal and Nutraceutical Plants and III Conference of National Institute of Science & Technology for Tropical Fruits, , Brazil.
    • Lapphanichayakool, P. , Sutheerawattananonda, M. , Limpeanchob, N. . Hypocholesterolemic effect of sericin derived oligopeptide in high cholesterol fed-rats (Poster and Full paper proceeding), . Poster Presentation: The 38th congress on Science and Technology of Thailand (STT38), Science for the future of mankind, , Chiangmai Thailand.
    • Yancheun, P. , Limpeanchob, N. . Oxidized low density lipoprotein induced oxidative stress and activated CREB in neuroblastoma cells (Poster and Full paper proceeding), . Poster Presentation: The 38th congress on Science and Technology of Thailand (STT38), Science for the future of mankind, , Chiangmai Thailand. .
    • Potential of Papaya Extract Against Alzheimers Disease in Cell Culture, . Oral Presentation: Thai Fruits-Functional Fruits; THAIFEX, World of Food Asia, , Impact Meung-Thong Thanee, Thailand.
    • Kaewkon, W. , Tiyaboonchai, W. , Pongcharoen, S. , Sutheerawattananonda, M. , Limpeanchob, N. . Chemopreventive Effect of Sericin Against Colon Cancer in Culture Colon Cancer Cell Lines, . Poster Presentation: The 6th International Congress on Chemistry for Innovation (PERCH-CIC Congress IV) , .
    • Duangjai, A. , Ingkaninan, K. , Limpeanchob, N. . Potential Mechanisms of Hypocholesterolemic Effect of Thai Plants, . Poster Presentation: The 6th International Congress on Chemistry for Innovation (PERCH-CIC Congress IV) , .
    • Neuroprotective effect of Bacopa monnieri on beta-amyloid and glutamate-induced neurotoxicity in primary cortical cultures, . Poster Presentation: Southeast Asian Western Pacific Regional meeting of Pharmacologists (SEAWP-RMP), , Australia.
    • In vitro and in vivo activation of nuclear factor of activated T cells (NFAT) in neurons, . Oral Presentation: 19th Annual Graduate Honors Symposium School of Pharmacy, , University of Kansas, Kansas, USA.
    • In vitro and in vivo activation of nuclear factor of activated T cells (NFAT) in neurons, . Poster Presentation: 33rd Society for Neuroscience Annual Meeting, , , New Orleans, LA, USA.
    • Calcium signaling in neurons through nuclear factor of activated T cells (NFAT), . Poster Presentation: 32nd Society for Neuroscience Annual Meeting, , , Orlando, FL, USA.

      5.05 Patent | Petty Patent
    • . International, Silk based bioactive oligopeptide compositions and manufacturing process therefor, (WO 2013/032411 A1) (Co-inventor) .
    • . International, Method for extracting silk extract containing lutein, (WO 2012/091683 A1) (Co-inventor) .

      5.06 Accomplished Research Work
    • 2014 . Immunomodulatory activity of beta-glucan from Rassula delica Fr. , Principle Investigator; (Naresuan University, National Research Council of Thailand 2013-2014).
    • 2014 . Effect of oxidized low density lipoprotein on acetylcholinesterase in culture neurons , Principle Investigator; (Naresuan University, National Research Council of Thailand 2014).
    • 2014 . Effect of oxidized low-density lipoproteins on amyloid precursor protein processing , Principle Investigator; (Naresuan University, National Research Council of Thailand 2012-2014).
    • 2011 . Development of nutraceutical and pharmaceutical products from lutein extracted from Bombyx mori cocoons and sericin derivatives , Co-Investigator; (Agricultural Research Development Agency (Public Organization Oct 2008-2011).
    • 2011 . Immunomodulatory activity of beta-glucan from edible mushroom , Principle Investigator; (Office of the Higher education commission 2011).
    • 2011 . Oxidized low-density lipoproteins induce neurotoxicity and reduce memory transcription factor in neuroblastoma cells , Principle Investigator; (Naresuan University, National Research Council of Thailand 2011).
    • 2011 . Piperine and its derivatives inhibit low-density lipoproteins oxidation and uptake by macrophage , Co-Investigator; (Naresuan University, National Research Council of Thailand 2011).
    • 2011 . Potential of guava, papaya, pomelo, and pineapple on lipid digestion , Principle Investigator; (Thailand Research Fund 2011).
    • 2010 . Mechanism of apoptosis induced by Derris scandens Benth in colon cancer cells , Principle Investigator; (Naresuan University, National Research Council of Thailand 2010).
    • 2010 . Piperine regulates protein expression in Caco-2 cells , Principle Investigator; (Naresuan University, National Research Council of Thailand 2010).
    • 2009 . Chemoprevention of colon cancer by Thai plants using cell lines , Principle Investigator; (Naresuan University, National Research Council of Thailand 2009).
    • 2009 . Inhibition of cholesterol absorption by Thai plants in intestinal cell culture , Principle Investigator; (Naresuan University, National Research Council of Thailand 2009).
    • 2008 . Cholesterol absorption inhibitory effect of ripe banana in intestinal cell line , Co-Investigator; (The Thailand Research Fund 2008).
    • 2008 . Effect of papaya extract on AChE activity and soluble sAPP secretion , Principle Investigator; (The Thailand Research Fund 2008).
    • 2008 . Hepatoprotective effect of Curcuma longa in ethanol-induced rat hepatic injury , Principle Investigator; (Naresuan University, National Research Council of Thailand, 2008).
    • 2008 . Inhibition of cholesterol absorption by Thai plants using intestinal cell cultures , Principle Investigator; (The Thailand Research Fund 2008).
    • 2008 . Neuroprotective effect of Thai herbs against free radical-induced cell damage in primary neuronal cultures , Principle Investigator; (Naresuan University, National Research Council of Thailand).
    • 2000 . Development of Heamorrhagic Septicaemia Vaccine , Co-Investigator; (National Center of Genetic Engineering and Biotechnology (BIOTEC), Thailand).
    • 2000 . Effect of nicotine on pCREB level in primary cortical culture , Principal Investigator; (Pharmaceutical Sciences, Naresuan University).
    • 2000 . Efficacy and toxicity of amphotericin B-chitosan nanoparticles , Principal Investigator; (National Center of Genetic Engineering and Biotechnology (BIOTEC), Thailand).
    • 2000 . Neuroprotective effect of Bacopa monneiri on Alzheimers peptide A 25-32-treated cultured cortical neurons , Principal Investigator; (National Research Council of Thailand).
    • 2000 . Screening for neuroprotective activity of plants used in Thai traditional rejuvenating and neurotonic remedies: a drug discovery effort against Alzheimers disease , Principal Investigator; (Naresuan University, National Research Council of Thailand).
    • 2000 . Study of sericin as dietary supplement for colorectal cancer and coronary artery disease (CAD) prevention , Co-Investigator; (The Thailand Research Fund) .

    7. Ongoing Research

    • Pharmacology : studying of nutraceutical, pharmacological effects and toxicities of plants and natural components using cell-based assays.
    • Neuroscience research : studying of neuroprotective effects of certain substances in neuronal cell cultures, particularly cortical and hippocampal neurons.
    • Clinical research : testing the pharmacological effect of nutraceutical products in human volunteers
    • Ongoing Research: Inhibitory effect of Alpinia galanga (L .) extracts on in vitro lipid digestion model
    • Ongoing Research: Neuroprotective effect of Bacopa monnieri extract on oxidized low density lipoprotein induced neurotoxicity in culture
    • Ongoing Research: Study of vegetable water extracts on lipid digestion in vitro model
    • Ongoing Research: Development of product from vegetables and herbs for fat digestion inhibition

    8. Awards

    • 2016 : Outstanding Academic Employee of the Year 2013 , Naresuan University
    • 2012 : The Award of The Royal Golden Jubilee for Ph.D. supervisor (15 series) ,  

    10. Training

    • 21 ¹ 2557 , Human Subject Protection Course and Standard Operating Procedures , Naresuan University, Phitsanulok , Thailand
    • 21 - 22 Ҥ 2557 , Human Subject Protection Course , Naresuan University, Phitsanulok , Thailand
    • 29 - 30 ¹ 2556 , Good Clinical Practice: ICH GCP, Basic GCP training program , Naresuan University, Phitsanulok , Thailand
    • 27 - 29 Զع¹ 2555 , Standard course in clinical trial (International), , Faculty of Medicine, Chulalongkorn University, Bangkok , Thailand
    • 17 - 21 Ȩԡ¹ 2551 , The Workshop on FISH and SKY in Cancer Research , Faculty of Medical Science, Naresuan University, Phitsanulok , Thailand
    • 25 - 6 Զع¹ 2551 , Training for Trainers on Care & Use of Animal Scientific Purposes , Chonburi , Thailand



  • Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, 65000, Thailand